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Experimental models have examined its influence on vascular endothelial growth factor receptor-2 (VEGFR2) signaling, including activation of downstream VEGFR2AkteNOS pathways associated with endothelial cell proliferation and vascular signaling processes

Fat loss While some evidence points to IGF-1s involvement in nutrient partitioning within the body, promoting lean tissue growth over fat storage, this is far less researched than its anabolic effects on muscle tissue

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